diff --git a/changelogs/fragments/85966-psrp-readtimeout.yml b/changelogs/fragments/85966-psrp-readtimeout.yml
new file mode 100644
index 00000000000..68fb53cabfb
--- /dev/null
+++ b/changelogs/fragments/85966-psrp-readtimeout.yml
@@ -0,0 +1,2 @@
+bugfixes:
+  - psrp - ReadTimeout exceptions now mark host as unreachable instead of fatal (https://github.com/ansible/ansible/issues/85966)
diff --git a/lib/ansible/plugins/connection/psrp.py b/lib/ansible/plugins/connection/psrp.py
index cef9b4346d7..0bc5085a7e9 100644
--- a/lib/ansible/plugins/connection/psrp.py
+++ b/lib/ansible/plugins/connection/psrp.py
@@ -331,7 +331,7 @@ try:
     from pypsrp.host import PSHost, PSHostUserInterface
     from pypsrp.powershell import PowerShell, RunspacePool
     from pypsrp.wsman import WSMan
-    from requests.exceptions import ConnectionError, ConnectTimeout
+    from requests.exceptions import ConnectionError, ConnectTimeout, ReadTimeout
 except ImportError as err:
     HAS_PYPSRP = False
     PYPSRP_IMP_ERR = err
@@ -479,11 +479,16 @@ class Connection(ConnectionBase):
             pwsh_in_data = in_data
             display.vvv(u"PSRP: EXEC %s" % script, host=self._psrp_host)
 
-        rc, stdout, stderr = self._exec_psrp_script(
-            script=script,
-            input_data=pwsh_in_data.splitlines() if pwsh_in_data else None,
-            arguments=script_args,
-        )
+        try:
+            rc, stdout, stderr = self._exec_psrp_script(
+                script=script,
+                input_data=pwsh_in_data.splitlines() if pwsh_in_data else None,
+                arguments=script_args,
+            )
+        except ReadTimeout as e:
+            raise AnsibleConnectionFailure(
+                "HTTP read timeout during PSRP script execution"
+            ) from e
         return rc, stdout, stderr
 
     def put_file(self, in_path: str, out_path: str) -> None: