diff --git a/changelogs/fragments/65051-regex-replace-multiline.yaml b/changelogs/fragments/65051-regex-replace-multiline.yaml
new file mode 100644
index 00000000000..3ce017cffdb
--- /dev/null
+++ b/changelogs/fragments/65051-regex-replace-multiline.yaml
@@ -0,0 +1,2 @@
+minor_changes:
+- regexp_replace filter - add multiline support for regex_replace filter (https://github.com/ansible/ansible/issues/61985)
diff --git a/docs/docsite/rst/user_guide/playbooks_filters.rst b/docs/docsite/rst/user_guide/playbooks_filters.rst
index 967d5185c6c..bb53b154ed3 100644
--- a/docs/docsite/rst/user_guide/playbooks_filters.rst
+++ b/docs/docsite/rst/user_guide/playbooks_filters.rst
@@ -1396,6 +1396,9 @@ To replace text in a string with regex, use the "regex_replace" filter::
     # convert "localhost:80" to "localhost"
     {{ 'localhost:80' | regex_replace(':80') }}
 
+    # change a multiline string
+    {{ var | regex_replace('^', '#CommentThis#', multiline=True) }}
+
 .. note:: If you want to match the whole string and you are using ``*`` make sure to always wraparound your regular expression with the start/end anchors.
    For example ``^(.*)$`` will always match only one result, while ``(.*)`` on some Python versions will match the whole string and an empty string at the
    end, which means it will make two replacements::
diff --git a/lib/ansible/plugins/filter/core.py b/lib/ansible/plugins/filter/core.py
index d2ae68a2441..52721e53808 100644
--- a/lib/ansible/plugins/filter/core.py
+++ b/lib/ansible/plugins/filter/core.py
@@ -123,15 +123,16 @@ def fileglob(pathname):
     return [g for g in glob.glob(pathname) if os.path.isfile(g)]
 
 
-def regex_replace(value='', pattern='', replacement='', ignorecase=False):
+def regex_replace(value='', pattern='', replacement='', ignorecase=False, multiline=False):
     ''' Perform a `re.sub` returning a string '''
 
     value = to_text(value, errors='surrogate_or_strict', nonstring='simplerepr')
 
+    flags = 0
     if ignorecase:
-        flags = re.I
-    else:
-        flags = 0
+        flags |= re.I
+    if multiline:
+        flags |= re.M
     _re = re.compile(pattern, flags=flags)
     return _re.sub(replacement, value)
 
diff --git a/test/integration/targets/filter_core/files/foo.txt b/test/integration/targets/filter_core/files/foo.txt
index a5839cee958..55fba527902 100644
--- a/test/integration/targets/filter_core/files/foo.txt
+++ b/test/integration/targets/filter_core/files/foo.txt
@@ -61,6 +61,9 @@ TODO: realpath follows symlinks.  There isn't a test for this just now.
 TODO: add tests for set theory operations like union
 
 regex_replace = bar
+# Check regex_replace with multiline
+#bar
+#bart
 regex_search = 0001
 regex_findall = "['car', 'tar', 'bar']"
 regex_escape = \^f\.\*o\(\.\*\)\$
diff --git a/test/integration/targets/filter_core/templates/foo.j2 b/test/integration/targets/filter_core/templates/foo.j2
index 55893cc1321..9d895fdcedc 100644
--- a/test/integration/targets/filter_core/templates/foo.j2
+++ b/test/integration/targets/filter_core/templates/foo.j2
@@ -55,6 +55,8 @@ TODO: realpath follows symlinks.  There isn't a test for this just now.
 TODO: add tests for set theory operations like union
 
 regex_replace = {{ 'foo' | regex_replace('^foo', 'bar') }}
+# Check regex_replace with multiline
+{{ '#foo\n#foot' | regex_replace('^#foo', '#bar', multiline=True) }}
 regex_search = {{ 'test_value_0001' | regex_search('([0-9]+)$')}}
 regex_findall = "{{ 'car\ntar\nfoo\nbar\n' | regex_findall('^.ar$', multiline=True) }}"
 regex_escape = {{ '^f.*o(.*)$' | regex_escape() }}